Description
产品说明
| 所属分类 | 微生物 > 模式菌株 |
|---|---|
| 品牌 / 来源 | CS-BIC | 中科生信 |
| 应用 | 细胞提取物能够通过环化作用将苯乙酰-L-半胱氨酰-D-缬氨酸转变为苄青霉素 |
| 培养基 | ATCC Medium 196: Yeast malt extract agar 酵母麦芽汁琼脂 ATCC Medium 1877: ISP Medium 1 ISP培养基1号 |
| 存储人 | CE Higgens |
| 出品公司 | ATCC |
| 分离来源 | 土壤，南美 |
| 参考文献 | Luengo JM, et al. Cyclization of phenylacetyl-L-cysteinyl-D-valine to benzylpenicillin using cell-free extracts of Streptomyces clavuligerus. J. Antibiot. 39: 1144-1147, 1986. PubMed: 3759664 Baldwin JE, et al. Isolation and partial characterization of ACV synthetase from Cephalosporium acremonium and Streptomyces clavuligerus. Evidence for the presence of phosphopantothenate in ACV synthetase. J. Antibiot. 44: 241-248, 1991. PubMed: 2010361 Zhang J, Demain AL. Regulation of ACV synthetase activity in the beta-lactam biosynthetic pathway of carbon sources and their metabolites. Arch. Microbiol. 158: 364-369, 1992. Howarth TT, et al. Antibiotics. US Patent 4,525,352 dated Jun 25 1985 Perez-Llarena FJ, et al. A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Strptomyces clavuligerus: amplification results in overproduction of both beta-Lactam compounds. J. Bacteriol. 179: 2053-2059, 1997. PubMed: 9068654 |
| 模式菌株 | 是 |
| 生长条件 | 30 ℃, 有氧 |
| 菌株特点 | ATCC 27064是Streptomyces clavuligerus，带小棒链霉菌。 Nucleotide (GenBank) : A38835 Sequence 2 from Patent WO9412654. Nucleotide (GenBank) : A39664 Sequence 1 from Patent WO9418326. Nucleotide (GenBank) : A42941 Sequence 2 from Patent WO9503416. Nucleotide (GenBank) : AJ000671 Streptomyces clavuligerus car and claR genes. Nucleotide (GenBank) : AJ001743 Streptomyces clavuligerus pcd, cmcT and pbp2 genes. Nucleotide (GenBank) : Z81324 S.clavuligerus ccaR and blp genes and open open reading frame. Nucleotide (GenBank) : AF038457 Streptomyces clavuligerus strain ATCC 27064 plasmid pSCL2 terminus. Nucleotide (GenBank) : L06213 Streptomyces clavuligerus clavaminate synthase 1 (cs1) gene, complete cds. Nucleotide (GenBank) : Z49111 Streptomyces clavuligerus arginine biosynthesis cluster (argCJBDRGH genes). Nucleotide (GenBank) : AJ238211 Streptomyces clavuligerus ORF1, encoding a protein involved in clavulanic acid biosynthesis. |
| 菌株类型 | Streptomyces clavuligerus，带小棒链霉菌 |
| 菌种又名 | [NRRL 3585] |
| 菌种名称 | ATCC 27064, ATCC27064 |
| 产品目录号 | 27064 |
| 基因组序列号 | ABJH00000000, CM000913, CM001015 |
| 生物安全等级 | 1 |
| 其他保藏库编号 | AS 4.1611 =ATCC 27064 =BCRC 11518 =CBS 226.75 =DSM 40751 =KCTC 9095 =NBRC 13307 |
| 基因组是否测序 | 是 |
| ATCC27064标准菌株基本信息 | ATCC ATCC 27064, ATCC27064 [NRRL 3585] Streptomyces clavuligerus，带小棒链霉菌 CE Higgens 土壤，南美 27064 AS 4.1611 =ATCC 27064 =BCRC 11518 =CBS 226.75 =DSM 40751 =KCTC 9095 =NBRC 13307 ATCC Medium 196: Yeast malt extract agar 酵母麦芽汁琼脂 ATCC Medium 1877: ISP Medium 1 ISP培养基1号 30 ℃, 有氧 1 ABJH00000000, CM000913, CM001015 是 是 细胞提取物能够通过环化作用将苯乙酰-L-半胱氨酰-D-缬氨酸转变为苄青霉素 ATCC 27064是Streptomyces clavuligerus，带小棒链霉菌。 Nucleotide (GenBank) : A38835 Sequence 2 from Patent WO9412654. Nucleotide (GenBank) : A39664 Sequence 1 from Patent WO9418326. Nucleotide (GenBank) : A42941 Sequence 2 from Patent WO9503416. Nucleotide (GenBank) : AJ000671 Streptomyces clavuligerus car and claR genes. Nucleotide (GenBank) : AJ001743 Streptomyces clavuligerus pcd, cmcT and pbp2 genes. Nucleotide (GenBank) : Z81324 S.clavuligerus ccaR and blp genes and open open reading frame. Nucleotide (GenBank) : AF038457 Streptomyces clavuligerus strain ATCC 27064 plasmid pSCL2 terminus. Nucleotide (GenBank) : L06213 Streptomyces clavuligerus clavaminate synthase 1 (cs1) gene, complete cds. Nucleotide (GenBank) : Z49111 Streptomyces clavuligerus arginine biosynthesis cluster (argCJBDRGH genes). Nucleotide (GenBank) : AJ238211 Streptomyces clavuligerus ORF1, encoding a protein involved in clavulanic acid biosynthesis. Luengo JM, et al. Cyclization of phenylacetyl-L-cysteinyl-D-valine to benzylpenicillin using cell-free extracts of Streptomyces clavuligerus. J. Antibiot. 39: 1144-1147, 1986. PubMed: 3759664 Baldwin JE, et al. Isolation and partial characterization of ACV synthetase from Cephalosporium acremonium and Streptomyces clavuligerus. Evidence for the presence of phosphopantothenate in ACV synthetase. J. Antibiot. 44: 241-248, 1991. PubMed: 2010361 Zhang J, Demain AL. Regulation of ACV synthetase activity in the beta-lactam biosynthetic pathway of carbon sources and their metabolites. Arch. Microbiol. 158: 364-369, 1992. Howarth TT, et al. Antibiotics. US Patent 4,525,352 dated Jun 25 1985 Perez-Llarena FJ, et al. A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Strptomyces clavuligerus: amplification results in overproduction of both beta-Lactam compounds. J. Bacteriol. 179: 2053-2059, 1997. PubMed: 9068654 |
Related
